And I never realized this, but think about it. I know of at least 3 or 3 Immune comprimised dogs now, all female and then I came across this article -
Hemolytic Anemia
This is a type of anemia. Hemolytic anemia in dogs is mainly an autoimmune disease. Hemolytic anemia in dogs prognosis depends a lot on the underlying reason of the anemia. This disorder mainly affects female dogs more than the male ones. Also, a few dog breeds like poodles, terriers, spaniels, etc. are more prone to this disorder. Reasons which will trigger hemolytic anemia in dogs are contamination due to zinc, bee venom, bee infection, etc.
Here if the link to the articla
www.buzzle.com/articles/anemia-in-dogs.html
I asked my Dr. again yesterday when I picked up Naomi if this was not triggered by a bee sting and she said without a blink of her eye, that she was very positive that the onset of the Lyme diease is the cause of Naomi's AIHA.
Friday, October 8, 2010
Cannot sleep -
Naomi's breathing and heart rate are going so fast. I cannot sleep because I keep listening for her breathing, I am so afraid her little heart is going to just get too tired and stop.
So I took her outside and she relieved herself and then we came in and she drank her pedialite and is resting again. I might try and doze off in a while, but I just cannot.
Naomi can take Winston's blood just this one time, if she needs another trans fusion we will have to do a cross match. The second one would make her sensitive to his blood and possible further complcations.
Actually there are 8 groups.
This is from Cornell University
Canine blood groups
There are 8 major blood groups in the dog, labeled as DEA (dog erythrocyte antigen) 1 to 8. These are illustrated in the table below. The major antigens are DEA 1.1 and DEA 1.2. Dogs can be positive for either (not both) DEA 1.1 or 1.2 or are negative for both. Naturally occurring antibodies occur in 20% of DEA 3-negative, 10% of DEA 5-negative, and 20-50% of DEA 7-negative dogs.
Acute hemolytic transfusion reactions only occur in DEA 1.1 and 1.2 negative dogs. As these dogs do not have naturally occurring antibodies, a reaction will only be seen after sensitization of the dog through exposure to DEA 1.1 or 1.2 positive blood (antibody production takes 7-10 days after exposure). The normal lifespan of compatible transfused erythrocytes in dogs is approximately 21 days. In an acute hemolytic transfusion reaction, the lifespan of incompatible transfused erythrocytes ranges from minutes to 12 hours. Although DEA 3-, 5- and 7-negative dogs do have naturally occurring antibodies to DEA 3, 5 and 7 positive red cells, these blood groups do not incite severe hemolytic reactions. Rather, transfusion of incompatible blood is hemolysed more rapidly (within 4 to 5 days) than compatible blood would be (so-called delayed hemolytic reaction). Therefore, crossmatching in dogs does not need to be done on the first transfusion. Neonatal isoerythrolysis has been reported in DEA 1 negative female dogs (previously sensitized to DEA 1 positive cells) mated to DEA 1.1 positive male dogs.
DEA "old" name" Population Natural Transfusion Sinificance
group incidence* antibody
1.1 A1 40-60% No Acute hemolytic reaction
1.2 A2 10-20% No Acute hemolytic reaction
3 B 5-20% Yes Delayed hemolysis
4 C 85-98% No None
5 D 10-25% Yes Delayed hemolysis
6 F 98-99% No Unknown
7 Tr 10-45% Yes Delayed hemolysis
8 He 40% No Unknown
* Incidence is breed-dependent, e.g., most Greyhounds are negative for DEA 1.1 (explaining their choice as blood donors) but are positive for DEA 3, whilst large numbers of Labrador retrievers are DEA 1.1 positive.
I tried to do the chart and it came out scrunched so here is the link for this page with the Blood Chart
Link -
ahdc.vet.cornell.edu/clinpath/modules/coags/typek9.htm
Naomi's breathing and heart rate are going so fast. I cannot sleep because I keep listening for her breathing, I am so afraid her little heart is going to just get too tired and stop.
So I took her outside and she relieved herself and then we came in and she drank her pedialite and is resting again. I might try and doze off in a while, but I just cannot.
Naomi can take Winston's blood just this one time, if she needs another trans fusion we will have to do a cross match. The second one would make her sensitive to his blood and possible further complcations.
Actually there are 8 groups.
This is from Cornell University
Canine blood groups
There are 8 major blood groups in the dog, labeled as DEA (dog erythrocyte antigen) 1 to 8. These are illustrated in the table below. The major antigens are DEA 1.1 and DEA 1.2. Dogs can be positive for either (not both) DEA 1.1 or 1.2 or are negative for both. Naturally occurring antibodies occur in 20% of DEA 3-negative, 10% of DEA 5-negative, and 20-50% of DEA 7-negative dogs.
Acute hemolytic transfusion reactions only occur in DEA 1.1 and 1.2 negative dogs. As these dogs do not have naturally occurring antibodies, a reaction will only be seen after sensitization of the dog through exposure to DEA 1.1 or 1.2 positive blood (antibody production takes 7-10 days after exposure). The normal lifespan of compatible transfused erythrocytes in dogs is approximately 21 days. In an acute hemolytic transfusion reaction, the lifespan of incompatible transfused erythrocytes ranges from minutes to 12 hours. Although DEA 3-, 5- and 7-negative dogs do have naturally occurring antibodies to DEA 3, 5 and 7 positive red cells, these blood groups do not incite severe hemolytic reactions. Rather, transfusion of incompatible blood is hemolysed more rapidly (within 4 to 5 days) than compatible blood would be (so-called delayed hemolytic reaction). Therefore, crossmatching in dogs does not need to be done on the first transfusion. Neonatal isoerythrolysis has been reported in DEA 1 negative female dogs (previously sensitized to DEA 1 positive cells) mated to DEA 1.1 positive male dogs.
DEA "old" name" Population Natural Transfusion Sinificance
group incidence* antibody
1.1 A1 40-60% No Acute hemolytic reaction
1.2 A2 10-20% No Acute hemolytic reaction
3 B 5-20% Yes Delayed hemolysis
4 C 85-98% No None
5 D 10-25% Yes Delayed hemolysis
6 F 98-99% No Unknown
7 Tr 10-45% Yes Delayed hemolysis
8 He 40% No Unknown
* Incidence is breed-dependent, e.g., most Greyhounds are negative for DEA 1.1 (explaining their choice as blood donors) but are positive for DEA 3, whilst large numbers of Labrador retrievers are DEA 1.1 positive.
I tried to do the chart and it came out scrunched so here is the link for this page with the Blood Chart
Link -
ahdc.vet.cornell.edu/clinpath/modules/coags/typek9.htm
Update -
ok, we are home and she is resting. I gotta get her medicine ready and her food ready and her water. The whole job is about 90 min. long, but 90 min I don't mind. Her tail wag for the water is worth it and her fight to not eat is worth it. Tells me she has the strength to fight with me over things. :)
ok, we are home and she is resting. I gotta get her medicine ready and her food ready and her water. The whole job is about 90 min. long, but 90 min I don't mind. Her tail wag for the water is worth it and her fight to not eat is worth it. Tells me she has the strength to fight with me over things. :)
Update -
Back from the Dr..
I dropped Winston and Naomi off and pick them up tonight.
The stats on Naomi's red blood count (RBC) is devestating
Normal dog RBC is - Red Blood Cell Count (RBC), 5.5 - 8.5 X 100000/L
Naomi is 1.x100000/L
If this does not work I do not see how she can survive. The Dr. said that she should not be alive with that low of a RBC.
If ever you are going to pray, Naomi really needs them today
Back from the Dr..
I dropped Winston and Naomi off and pick them up tonight.
The stats on Naomi's red blood count (RBC) is devestating
Normal dog RBC is - Red Blood Cell Count (RBC), 5.5 - 8.5 X 100000/L
Naomi is 1.x100000/L
If this does not work I do not see how she can survive. The Dr. said that she should not be alive with that low of a RBC.
If ever you are going to pray, Naomi really needs them today
Update -
Naomi is awake, she has had her water and Gerber baby food and 1/3 of her prednisone so far.
She seems very alert and her gums are a tinge more pink and her eyes are still alittle yellow, but not like yesterday..
I am still going to go through with the blood transfusion. I believe in my heart that Winston's blood is really going to turn the tables on this diease and make Naomi well again.
Naomi is awake, she has had her water and Gerber baby food and 1/3 of her prednisone so far.
She seems very alert and her gums are a tinge more pink and her eyes are still alittle yellow, but not like yesterday..
I am still going to go through with the blood transfusion. I believe in my heart that Winston's blood is really going to turn the tables on this diease and make Naomi well again.
Update -
Naomi has taken a step backward since this morning.
The whites of her eyes have turned yellow and she is not getting better.
So Winston is to be her Hero.
Tomorrow he goes in with her and gives her a desperately needed blood transfusion. His healthy, fatty, oxygen rich blood is our last hope to her survival.
This Nobel, Wonderful Standard Poodle is again called upon to save a life. His first time was with a little mentally challenged little girl, who was also deaf was attacked by pitbulls and her terror of dogs paralyzed her, by the end of 6 months with Winston's kindness she was no longer fearful and hugged him all of the time.
He is my heartdog and Naomi's last chance at survival.
What I have not told anyone is that Winston experienced his own crisis just a few weeks ago when I found a nerfball sized lump on his side by his tuck. I was terrified it was cancer and took him in for a biopsy. It turned out not to be cancer, but a fat lump with an infection in the center of it. So with very strong antibiotics he is cleared and with that past the Vet said that his blood would be best for Naomi as it is very healthy, rich and thick.
Naomi has taken a step backward since this morning.
The whites of her eyes have turned yellow and she is not getting better.
So Winston is to be her Hero.
Tomorrow he goes in with her and gives her a desperately needed blood transfusion. His healthy, fatty, oxygen rich blood is our last hope to her survival.
This Nobel, Wonderful Standard Poodle is again called upon to save a life. His first time was with a little mentally challenged little girl, who was also deaf was attacked by pitbulls and her terror of dogs paralyzed her, by the end of 6 months with Winston's kindness she was no longer fearful and hugged him all of the time.
He is my heartdog and Naomi's last chance at survival.
What I have not told anyone is that Winston experienced his own crisis just a few weeks ago when I found a nerfball sized lump on his side by his tuck. I was terrified it was cancer and took him in for a biopsy. It turned out not to be cancer, but a fat lump with an infection in the center of it. So with very strong antibiotics he is cleared and with that past the Vet said that his blood would be best for Naomi as it is very healthy, rich and thick.
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