Friday, October 8, 2010

Cannot sleep -
Naomi's breathing and heart rate are going so fast. I cannot sleep because I keep listening for her breathing, I am so afraid her little heart is going to just get too tired and stop.
So I took her outside and she relieved herself and then we came in and she drank her pedialite and is resting again. I might try and doze off in a while, but I just cannot.
Naomi can take Winston's blood just this one time, if she needs another trans fusion we will have to do a cross match. The second one would make her sensitive to his blood and possible further complcations.

Actually there are 8 groups.
This is from Cornell University

Canine blood groups

There are 8 major blood groups in the dog, labeled as DEA (dog erythrocyte antigen) 1 to 8. These are illustrated in the table below. The major antigens are DEA 1.1 and DEA 1.2. Dogs can be positive for either (not both) DEA 1.1 or 1.2 or are negative for both. Naturally occurring antibodies occur in 20% of DEA 3-negative, 10% of DEA 5-negative, and 20-50% of DEA 7-negative dogs.

Acute hemolytic transfusion reactions only occur in DEA 1.1 and 1.2 negative dogs. As these dogs do not have naturally occurring antibodies, a reaction will only be seen after sensitization of the dog through exposure to DEA 1.1 or 1.2 positive blood (antibody production takes 7-10 days after exposure). The normal lifespan of compatible transfused erythrocytes in dogs is approximately 21 days. In an acute hemolytic transfusion reaction, the lifespan of incompatible transfused erythrocytes ranges from minutes to 12 hours. Although DEA 3-, 5- and 7-negative dogs do have naturally occurring antibodies to DEA 3, 5 and 7 positive red cells, these blood groups do not incite severe hemolytic reactions. Rather, transfusion of incompatible blood is hemolysed more rapidly (within 4 to 5 days) than compatible blood would be (so-called delayed hemolytic reaction). Therefore, crossmatching in dogs does not need to be done on the first transfusion. Neonatal isoerythrolysis has been reported in DEA 1 negative female dogs (previously sensitized to DEA 1 positive cells) mated to DEA 1.1 positive male dogs.

DEA "old" name" Population Natural Transfusion Sinificance
group incidence* antibody
1.1 A1 40-60% No Acute hemolytic reaction
1.2 A2 10-20% No Acute hemolytic reaction
3 B 5-20% Yes Delayed hemolysis
4 C 85-98% No None
5 D 10-25% Yes Delayed hemolysis
6 F 98-99% No Unknown
7 Tr 10-45% Yes Delayed hemolysis
8 He 40% No Unknown

* Incidence is breed-dependent, e.g., most Greyhounds are negative for DEA 1.1 (explaining their choice as blood donors) but are positive for DEA 3, whilst large numbers of Labrador retrievers are DEA 1.1 positive.

I tried to do the chart and it came out scrunched so here is the link for this page with the Blood Chart

Link -
ahdc.vet.cornell.edu/clinpath/modules/coags/typek9.htm

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